Immunoprophylactic polypeptides for schistosomiasis

Details Immunoprophylactic polypeptides for schistosomiasis Immunoprophylactic polypeptides for schistosomiasis

1991-07-09

1993-06-15

Wax, Robert A.

Drug, bio-affecting and body treating compositions

Lymphokine

530350, 530395, 435 693, 536 235, A61K 3900, C12N 1511

Patent

active

052195660

ABSTRACT:
Polypeptide epitopes are defined herein which when used as components of vaccine compositions, induced partial immunity to Schistosoma mansoni. The epitopes are found on the surface of schistosumula. The epitopes are part of larger proteins which are immunologically cross-reactive with myosin heavy chains from other species. However, anti-myosin antibodies directed against myosin molecules of other species are not cross-reactive with the surface epitopes of S. mansoni.

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