Immunopotentiator and method of manufacturing the same

Details Immunopotentiator and method of manufacturing the same Immunopotentiator and method of manufacturing the same

1995-07-12

1996-10-01

Rollins, John W.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Conjugate or complex

4352541, 4352561, 435911, 424 9461, 4242741, 4242781, A61K 3578, C12N 114

Patent

active

055609147

ABSTRACT:
In a method of producing an immunopotentiator, a plant tissue material is extracted with hot water, the insoluble material is filtered, and the filtrate thereof is treated with glucoamylase to decompose a starch, thereby obtaining a water-soluble polysaccharide. Ammonium sulfate is added in a culture filtrate obtained by culturing any one of Asp Oryzae of the Aspergillaceae and Lentinus edodes of the Basidiomycetes to obtain an enzyme complex from the precipitate. The water-soluble polysaccharide and the enzyme complex are added together to cause them to react at a pH of 4.5 for 30 to 60 minutes and then at a pH of 6.0 for 30 to 60 minutes, thereby biologically modifying the water-soluble polysaccharide.

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