Immunopotentiating agents and method

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Carbohydrate doai

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A61K 3173

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active

049719564

ABSTRACT:
A new immunopotentiating agent is now provided, which is useful for enhancing the immune response in living animals, including man, against the bacterial and fungan infections and also against the growth of tumors, and which comprises as active ingredient a water-soluble chitin-oligomer selected from di-N-acetyl-chitobiose, tri-N-acetyl-chitotriose, tetra-N-acetyl-chitotetraose, penta-N-acetyl-chitopentaose, hexa-N-acetyl-chitohexaose and hepta-N-acetyl-chitoheptaose, or a water-soluble chitosan-oligomer selected from chitobiose, chitotriose, chitotetraose, chitopentaose, chitohexaose and chitoheptaose. An immunopotentiating method using said water-soluble chitin-oligomer or said water-soluble chitosan-oligomer as the active ingredient is also provided.

REFERENCES:
patent: 3914413 (1975-10-01), Balassa
patent: 4605623 (1986-08-01), Malette et al.
The Merck Index 10th ed, 2017 (1983).
Chemical Abstracts 102: 84445j (Ajnomoto).
Chemical Abstracts 76: 35410a (1972).
Jnl of American Chemical Society 79, 5046-5049 (1957).
Proceedings of the National Academy of Sciences, vol. 74 (1) Jan. 1977, Kieda et al.
Patent Abstracts of Japan, Unexamined Applications, Section C, vol. 4, No. 77, Jun. 4, 1980.
Journal of the Chemical Society, Section C, Part II, 1970, London, Capon et al., pp. 1654-1655.

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