Immunopotentiating agent

Details Immunopotentiating agent Immunopotentiating agent

2005-12-20

2010-02-16

Huff, Sheela J (Department: 1643)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Peptide containing doai

C530S324000

Reexamination Certificate

active

07662781

ABSTRACT:
Satisfactory effects have not always been attained by immunotherapy having been tried, and reliance upon direct attack on cells by anticancer agents, radiation, etc has been inevitable. The present invention intends to provide a therapeutic method that ensures less side effects but higher efficacy than in conventional therapeutic methods through enhancing of immune strength inherently had by living organism. Thus, the present invention relates to an immunopotentiating agent comprising MIP-1α or its functional derivative as an active ingredient.

REFERENCES:
patent: 4705955 (1987-11-01), Mileikowsky
patent: 4847325 (1989-07-01), Shadle et al.
patent: 5616688 (1997-04-01), Cerami et al.
patent: 5824784 (1998-10-01), Kinstler et al.
patent: 5922597 (1999-07-01), Verfaillie et al.
patent: 5925568 (1999-07-01), Comer et al.
patent: 5977310 (1999-11-01), Namiki et al.
patent: 5985265 (1999-11-01), Kinstler et al.
patent: 6046309 (2000-04-01), Cerami et al.
patent: 6057123 (2000-05-01), Craig et al.
patent: 2006/0210531 (2006-09-01), Matsushima et al.
patent: 2008/0124307 (2008-05-01), Matsushima et al.
patent: 741472 (1999-03-01), None
patent: 2 036 197 (2001-09-01), None
patent: 0 136 792 (1985-04-01), None
patent: 0 154 316 (1985-09-01), None
patent: 0 210 761 (1987-02-01), None
patent: 0 442 724 (1991-08-01), None
patent: 0 510 356 (1992-10-01), None
patent: 0 898 968 (1999-03-01), None
patent: 1 013 276 (2000-06-01), None
patent: 0 923 566 (2003-10-01), None
patent: 0 816 381 (2004-01-01), None
patent: 1 563 847 (2005-08-01), None
patent: 61-178926 (1986-08-01), None
patent: 62-115280 (1987-05-01), None
patent: 5-117300 (1993-05-01), None
patent: 6-256394 (1994-09-01), None
patent: 8-511263 (1996-11-01), None
patent: 9-25298 (1997-01-01), None
patent: 10-513187 (1998-12-01), None
patent: 11-60499 (1999-03-01), None
patent: 11-310600 (1999-11-01), None
patent: 2000-157285 (2000-06-01), None
patent: 2000-517304 (2000-12-01), None
patent: 2004-194770 (2004-07-01), None
patent: 2004-196770 (2004-07-01), None
patent: WO-96/23794 (1996-08-01), None
patent: WO-96/28475 (1996-09-01), None
patent: WO-99/11666 (1999-03-01), None
patent: WO-00/47228 (2000-08-01), None
patent: WO-01/54727 (2001-08-01), None
patent: WO-01/83548 (2001-11-01), None
patent: WO-2004/024088 (2004-03-01), None
Burgess et al, Journal of Cell Biology vol. 111 Nov. 1990 2129-2138).
Lazar et al Molecular and Celular Biology vol. 8 p. 1247 (1988).
Taruki et al., “Mobilization of Dendritic Cells Into Solid Tumour by Administration of Styrene-maleic acid (SMA) Copolymer Conjugated MIP-1alpha (SMIP) in Mice,” Seikagaku, vol. 76, No. 8, 2004, pp. 986.
Menten et al., “Macrophage inflammatory protein-1,” Cytokine Growth Factor Rev., vol. 13, 2002, pp. 455-481.
Horiuchi et al., “Abscopal effect o Mitometa Shocho NK/T Saibo Lymphoma,” Rinsho Ketsueki, vol. 44, No. 9, 2003, pp. 940-945.
Demaria et al., “Ionizing Radiation Inhibition of Distant Untreated Tumors (Abscopal Effect) is Immune Mediated,” Int. J. Radiat. Oncol. Biol. Phys., vol. 58, No. 3, 2004, pp. 862-870.
Gazzaniga et al., “Inflammatory Changes after Cryosurgery-Induced Necrosis in Human Melanoma Xenografted in Nude Mice,” J. Invest. Dermatol., vol. 116, No. 5, 2001, pp. 664-671.
Wu et al., “Activated Anti-tumor Immunity in Cancer Patients after High Intensity Focused Ultrasound Ablation,” Ultrasound in Med. & Biol., vol. 30, No. 9, 2004, pp. 1217-1222.
English translation of the International Preliminary Report on Patentability dated Feb. 14, 2008, issued in connection with International Application No. PCT/JP2005/023884 filed Dec. 20, 2005.
Abuchowski et al., Cancer Biochem Biophys., vol. 7, pp. 175-186 (1984).
Yoshimoto et al. Jpn. J. Cancer Res. (Gann), vol. 77, pp. 1264-1270 (Dec. 1986).
Inaba et al., J Exp. Med., vol. 176, pp. 1693-1702 (Dec. 1992).
Hunter at al. Blood, vol. 86, No. 12, pp. 4400-4408 (Dec. 15 1995).
Fujioka et al., Journal of Leukocyte Biology, vol. 58, pp. 90-98 (Jul. 1995).
Bernstein et al., British Journal of Haematology, vol. 99, pp. 888-895 (1997).
Caux et al. Blood, vol. 90, No. 4, pp. 1458-1470 (Aug. 15 1997).
Zhang et al., Blood, vol. 90, No. 12, pp. 4842-4853 (Dec. 15, 1997).
Hart. Blood. vol. 90, No. 9, pp. 3245-3287 (Nov. 1, 1997).
Gao et al., The Journal of Experimental Medicine, vol. 185, No. 11, pp. 1959-1968 (Jun. 2, 1997).
Caux et al., Dendritic Cells in Fundamental and Clinical Immunology, vol. 3, Series: Adv. Exp. Med. Biol., vol. 417, pp. 21-25 (1997).
Marshall et al., European Journal of Cancer, vol. 34, No. 7, pp. 1023-1029 (1998).
Clemons at al., Blood, vol. 92, No. 5, pp.1532-1540 (Sep. 1, 1998).
Broxmeyer et al., Blood Cells, Molecules, and Diseases, vol. 24, No. 2, pp. 14-30 (Jan. 31, 1998).
Banchereau et al., Nature, vol. 392, pp. 245-252 (Mar. 19 1998).
Zhang et al, Blood, vol. 92, No. 1, pp. 118-128 (Jul. 1, 1998).
Dieu et al., J. Exp. Med., vol. 188, No. 2, pp. 373-386 (Jul. 20, 1998).
Zhang et al., Blood, vol. 93, No. 4, pp.1208-1220 (Feb. 15, 1999).
Ogata et al., Blood, vol. 93, No. 10, pp. 3225-3232 (May 15, 1999).
Zhang et al., Blood, vol. 95, No. 1, pp. 138-146 (Jan. 1, 2000).
Klein et al., J. Exp. Med., vol. 191, No. 10. pp. 1699-1708 (May 15, 2000).
Sallusto et al., Immunological Reviews, vol. 177, pp. 134-140 (2000).
Ali et al., The Journal of Biological Chemistry, vol. 275, No, 16, pp. 11721-11727 (Apr. 21, 2000).
Sozzani et al., Journal of Clinical Immunology, vol. 20, No. 3, pp. 151-160 (2000).
Allavena et al., Immunological Reviews, vol. 177, pp. 141-149 (2000).
Inaba, Cell Technology, vol. 19, No. 9, pp. 1282-1286 (2000).
Kawamoto et al., Cell Technology, vol. 19, No. 9, pp. 1289-1293 (2000).
Iyoda et al., Cell Technology, vol. 19 No. 9. pp. 1311-1317 2000.
Nakano, Cell Technology, vol. 19 No. 9, pp. 1304-1310 (2000).
Chemokine Handbook, front page, pp. 68-70, 84-86, 87-90, and publication data, Edited by O. Yosie et al., (Nov. 20, 2000).
Lin et al, J. Exp. Med., vol. 192, No. 4, pp. 587-593 (Aug. 21, 2000).
Takayama et al., Molecular Cell Therapy, vol. 2, No, 6, p. 53-56 (2001).
Yoneyama et al., J. Exp. Med., vol, 193. No. 1, pp. 35-49 (Jan. 1. 2001).
Uwatoku et al., Gastroenterology, vol. 121, pp. 1460-1472 (2001).
Zoffmann et al, J. Med. Chem., vol. 44, pp. 215-222 (2001).
Nomiyama et al., International Immunology, vol. 13, No. 8, pp. 1021-1029 (Mar. 1, 2001).
Weber et al., Blood, vol. 97, No. 4, pp. 1144-1146 (Feb. 15, 2001).
Dong et al., Biochemical and Biophysical Research Communications, vol. 298 pp. 675-686 (2002).
Yoneyama et al., J. Exp. Med., vol. 195, No. 10, pp. 1257-1266 (May 20, 2002).
Steinman et al., The Journal of Clinical Investigation, vol. 109, No. 12, pp. 1519-1526 (Jun. 2002).
Gillet et al J. Exp. Med., vol. 195, No. 7, pp. 953-958 (Apr. 1, 2002).
del Hoyo et al., Nature, vol. 415, pp. 1043-1047 (Feb. 28, 2002).
Matsuno, Progress of Medicine, vol. 200, No. 6 pp. 132-136 (2002).
Kuraoka et al., International Journal of Oncology, vol. 23, pp. 421-427 (2003).
O'Keeffe et al., Blood, vol. 101, No. 4, pp. 1453-1459 (Feb. 15, 2003).
Murai et al., Nature Immunology, vol. 4, No. 2, pp. 154-160 and 497 (Feb. 2003).
Zhang et al., Journal of the National Cancer Institute, vol. 96, No. 3, pp. 201-209 (Feb. 4, 2004).
McKay et al., Eur. J. Immunol., vol. 34, pp. 1011-1020 (2004).
Kaminski et al., Cancer Treatment Reviews, vol. 31, pp. 159-172 (2005).
Azuma et al., “Trial of Enhancing Anti-Tumor Immunity with Immunological Adjuvant”, vol. 9, Supplement. I, Feb. 1982, 40th Annual Meeting of the Japanese Cancer Association, Special Issue.
Nakano et al., “Induction of Dendritic Cell Precursors by MIP-1a and the Test of Their Effect on Tumor Regression”, Proceedings of the Japanese Society for Immunology, 2004, vol. 34, pp. 214.
Tanio et al., “Comparison of Antimetastatic Effect Against Lewis Lung Carcinoma After Intratumoral and Intravenous Injections of Cell-Wall Skeleton of Propionibacterium Acnes C7 in C57B/J6 Mice”, Gann, vol. 75, Mar. 1984, pp. 237-244.

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