Immunomodulator, cell adhesion inhibtor, and agent for treating,

Details Immunomodulator, cell adhesion inhibtor, and agent for treating, Immunomodulator, cell adhesion inhibtor, and agent for treating,

1996-05-06

1999-07-13

Criares, Theodore J.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

514444, 514422, 514397, 514383, 514374, 514372, 514352, 514359, 5142335, 514210, 514337, A61K 3135, A61K 3142, A61K 31535, A61K 31415

Patent

active

059227559

ABSTRACT:
##STR1## or a salt thereof exerts excellent effects on immunomodulation and cell adhesion inhibition, and is further expected to have the effect of relieving autoimmune diseases at a level comparable to that of steroids. and prevention of autoimmune diseases fundamentally caused by immunopathy or unusually accelerated cell adhesion, for example, chronic rheumatoid arthritis, systemic lupus erythematosus, scleroderma, mixed connective tissue disease,polyarteritis nodosa, polymyositis/dermatomyositis, Sjogren's syndrome, Behcet's disease, multiple sclerosis, autoimmune diabetes, Hashimoto's disease, psoriasis, primary myxedema, pernicious anemia, serious adynamia, ulcerative colitis, chronic active hepatitis, autoimmune hemolytic anemia idiopathic thrombocytopenic purpura and the like.

REFERENCES:
patent: 4954518 (1990-09-01), Takaro et al.
patent: 5196445 (1993-03-01), Doria et al.
Tanaka et al, J. Pharmacobio-Dyn., vol. 15, pp. 649-655 (1992).

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