Chemistry: natural resins or derivatives; peptides or proteins; – Peptides of 3 to 100 amino acid residues – 8 to 10 amino acid residues in defined sequence
Patent
1995-06-07
2000-08-08
Davenport, Avis M.
Chemistry: natural resins or derivatives; peptides or proteins;
Peptides of 3 to 100 amino acid residues
8 to 10 amino acid residues in defined sequence
530329, 530330, 530300, A61K 3800, C07K 500, C07K 700
Patent
active
061003808
ABSTRACT:
This invention provides peptides of the formula R'-Glx-Glx-Lys-R" in which Glx is Glu or Gln. In particular, this invention provides the peptides Thr-Ala-Glu-Glu-Lys and Thr-Pro-Glu-Glu-Lys. This invention also provides pharmaceutical compositions comprising these peptides. The peptides of this invention are useful for immunomodulation.
REFERENCES:
patent: 3803118 (1974-04-01), Bennett et al.
patent: 4002602 (1977-01-01), Goldstein
patent: 4010148 (1977-03-01), Goldstein
patent: 4038282 (1977-07-01), Hirschmann et al.
patent: 4077949 (1978-03-01), Goldstein
patent: 4079127 (1978-03-01), Goldstein et al.
patent: 4116951 (1978-09-01), Wang
patent: 4120951 (1978-10-01), Goldstein
patent: 4133804 (1979-01-01), Bach et al.
patent: 4148788 (1979-04-01), Wang
patent: 4167557 (1979-09-01), Goldstein
patent: 4261886 (1981-04-01), Goldstein et al.
patent: 4264571 (1981-04-01), Goldstein et al.
patent: 4297276 (1981-10-01), Goldstein et al.
patent: 4339427 (1982-07-01), Goldstein et al.
patent: 4353821 (1982-10-01), Birr et al.
patent: 4374828 (1983-02-01), Folkers et al.
patent: 4377511 (1983-03-01), Lopukhin et al.
patent: 4388234 (1983-06-01), Horecker
patent: 4389343 (1983-06-01), Horecker
patent: 4395404 (1983-07-01), Low et al.
patent: 4396605 (1983-08-01), Birr
patent: 4426324 (1984-01-01), Meienhofer
patent: 4427783 (1984-01-01), Newman et al.
patent: 4428938 (1984-01-01), Kisfaludy et al.
patent: 4442031 (1984-04-01), Felix et al.
patent: 4466918 (1984-08-01), Birr et al.
patent: 4470926 (1984-09-01), Birr et al.
patent: 4500450 (1985-02-01), Seipke et al.
patent: 4505853 (1985-03-01), Goldstein et al.
patent: 4517119 (1985-05-01), Felix et al.
patent: 4526717 (1985-07-01), Seipke et al.
patent: 4571336 (1986-02-01), Houck et al.
patent: 4599231 (1986-07-01), Milich et al.
patent: 4612365 (1986-09-01), Birr et al.
patent: 4614731 (1986-09-01), Horecker
patent: 4621135 (1986-11-01), Trainin et al.
patent: 4634682 (1987-01-01), Erickson et al.
patent: 4659694 (1987-04-01), Horecker
patent: 4696915 (1987-09-01), Horecker
patent: 4699898 (1987-10-01), Gottlieb
patent: 4711952 (1987-12-01), Kasafirek et al.
patent: 4722999 (1988-02-01), Handschumacher et al.
patent: 4751216 (1988-06-01), Gottlieb
patent: 4814434 (1989-03-01), Goldfarb
patent: 4826680 (1989-05-01), Jaeger
patent: 4904643 (1990-02-01), Brunetti et al.
patent: 4910296 (1990-03-01), Birr et al.
patent: 4983387 (1991-01-01), Goldstein et al.
U.S. application No. 07/415,283, Yakovlev et al., filed Dec. 14, 1988.
Anisimov et al. (1982) Mechanisms of Ageing and Development, 19:245-258.
Anisimov et al. (1989) Mechanisms of Ageing and Development, 49:245-257.
Belokrylov et al. (1978) Bulletin of Experimental Biology, No. 7, 84:56-58.
Belokrylov et al. (1977) Bulletin of Experimental Biology, No. 7, 86:51-53.
Bespaluv et al. (1989) Eksp. Onkol., Chemical Abstracts III, Abstract No. 146389R, 11(4) 23-6 (Russ).
Cytomedins (Bulletin), Apr. 13, 1990, Russia.
Gavrilenko et al. (1982) Bulletin of Experimental Biology, No. 4, 93:39-40.
Goldstein et al. (1972) Proc. Natl. Acad. Sci. USA, 69:1800-1803.
R. S. Chen (1989) Chemical Abstracts, vol. 111(7), Abstract No. 55230R.
Fauszt et al. (1975) Chemical Abstracts, vol. 82(11), Abstract No. 73453C.
Khmelnitskii et al. (1983), Bulletin of Experimental Biology, No. 6, 95:123-124.
Kuznik et al. (1982), Bulletin of Experimental Biology, No. 9, 94;27-29.
Kusnik et al. (1981) Bulletin of Experimental Biology, No. 9, 92:264-266.
Low et al. (1981) Proceedings of the National Academy of Science, 78:1162-1166.
Rodionov, et al. (1990) "The Immunocorrective Therapy of Pyoderma Caused by Staphylococci Multiply Resistant to Antibiotics"; Vestn. Dermatol. Venerol, 1:42-45 (Medline Abstract No. 90224329).
Solovev et al. (1977) Bulletin of Experimental Biology, No. 9, 84:355-358.
Solovev et al. (1983) Bulletin of Experimental Biology, No. 6, 95:123-124.
"Thymogen" (Bulletin), Nov. 11, 1989, published by Cytomed (Leningrad).
Yakovlev et al., (1990) Resistance Stress Regulation, Nauka Publishers (Leningrad), pp. 90-93, 174-205.
Two brochures in Russian (no English translation).
Remington's Pharmaceutical Science, 17th ed., Mack Publishing Co., Easton, PA (1985).
Stewart and Young, Solid Phase Peptide Synthesis, 2nd ed., Pierce Chemical Company (1984).
Maniatis et al., (1982) Molecular Cloning, A Laboratory Manual, Cold Spring Harbor Laboratory.
Tam et al. (1983) J. Am. Chem. Soc., 105:6442.
Declaration of Lawrence R. Green.
R.S. Chen; "Monte Carlo Simulations for the Study of Hemoglobin-Fragment Conformations"; Journal of Computational Chemistry, vol. 10, No. 4, pp. 488-494 (1989).
CA 78:43980, 1973, Bennett et al.
R.S. Chen, CA 111:55230r, 1989.
Hirschmann et al., CA 79:66820e, 1973.
Giori et al., CA 89:215752v, 1978.
Cola et al., CA 111: 129603p, 1989.
Green Lawrence R.
Ivanov Vadim T.
Khavinson Vladimir K.
Mikhaltsov Alexander N.
Mikhalyova Inessa I.
Cytran, Inc.
Davenport Avis M.
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