Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues – Lymphokines – e.g. – interferons – interlukins – etc.
Reexamination Certificate
2002-03-01
2009-10-13
Bunner, Bridget E (Department: 1647)
Chemistry: natural resins or derivatives; peptides or proteins;
Proteins, i.e., more than 100 amino acid residues
Lymphokines, e.g., interferons, interlukins, etc.
C435S069100, C435S070100, C435S325000, C435S471000, C435S320100, C536S023500
Reexamination Certificate
active
07601812
ABSTRACT:
The invention relates to active agents from parasitic worms, in particularSchistosoma mansoni, which induce a T-helper type 2 response (Th2 immune response).
REFERENCES:
patent: WO 02/085930 (2002-10-01), None
Haisch et al. Parasite Immunology, vol. 23, pp. 427-434, 2001.
Schramm et al. All of Abstracts for Sydney 2000.
Dunne et al. Trans R Soc Trop Med Hyg. 1981, pp. 54-71.
Kips et al. European Respiratory Journal. 2001. vol. 17, pp. 499-506.
Sambrook et al. Molecualr cloning, a laboratory Manual, 2nd edition, pp. 16.17-16.31, 1989.
Crystal, R. Science, 1995, vol. 270, pp. 404-410.
Verma et al. Nature, 1997, vol. 389, pp. 239-242.
Marshall, Science, 1995, vol. 269, pp. 1050-1054.
Rubanyi, Molecualr Aspects of Medicine, 2001, vol. 22, pp. 113-142.
Juengst, British Medical Journal, 2003, vol. 326, pp. 1410-1411.
Boros et al., “Delayed hypersensitivity-type granuloma formation and dermal reaction induced and elicited by a soluble factor isolated fromSchistosoma mansonieggs,”J. Exp. Med. 132:488-507 (1970).
Carter et al., “An electrophoretic analysis ofSchistosoma mansonisoluble egg antigen preparation,”J. Parasitol64:385-390 (1978).
Okano et al., “Induction of Th2 responses and IgE is largely due to carbohydrates functioning as adjuvants onSchistosoma mansoniegg antigens,”J. Immunol. 163:6712-6717 (1999).
Okano et al., “Lacto-N-fucopentaose III found onSchistosoma mansoniegg antigens functions as adjuvant for proteins by inducing Th2-type response,”J lmmunol. 167:442-450 (2001).
Patella et al., Endogenous superallergen protein Fv induces IL-4 secretion from human Fc epsilon RI+ cells through interaction with the VH3 region of IgE,J. Immunol. 161:5647-5655 (1998).
Patella et al., “HIV-1 gp 120 induces IL-4 and IL-13 release from human Fc epsilon RI+ cells through interaction with the VH3 region of IgE,”J. Immunol. 164:589-595 (2000).
Pearce, et al., “Downregulation of Th1 cytokine production accompanies induction of Th2 responses by a parasitic helminth,Schistosoma mansoni,” 173:159-166 (1991).J. Exp. Med.
Scott et al., “The role of T-cell subsets and cytokines in the regulation of infection,”Immunol. Today12:346-348 (1991).
Vella et al., CD4+ Th2 response induced bySchistosoma mansonieggs develops rapidly, through an early, transient, Th0-like stage,J. lmmunol. 148:2283-2290 (1992).
Velupillai et al., “Oligosaccharide-specific induction of interleukin 10 production by B220+ cells from schistosome-infected mice: a mechanism for regulation of CD4+ T-cell subsets,”Proc. Natl. Acad. Sci. USA91:18-22 (1994).
D. W. Dunne et al., “The stage-, strain- and species-specificity of aSchistosoma mansoniegg antigen fraction (CEF6) with serodiagnostic potential,” Transactions of the Royal Society of Tropical Medicine and Hygiene (1984) 78, 460-470.
D. W. Dunne et al., “The purification, characterization, serological activity and hepatotoxic properties of two cationic glycoproteins (α1and ω1) fromSchistosoma mansonieggs,” Parasitology (1991), 103, 225-236.
McLaren et al., “Serodiagnosis of humanSchistosoma mansoniinfections: enchanced sensitivity and specificity in ELISA using a fraction containingS. mansoniegg antigens ω1and α1,” Transactions of the Royal Society of Tropical Medicine and Hygeine, vol. 75, No. 1, 1981.
Schramm et al., “IPSE/alpha-1: A major immunogenic component secreted fromSchistosoma mansoniEggs,” Molecular & Biochemical Parasitology 147 (2006) 9-19.
Falcone Franco
Gronow Achim
Haas Helmut
Haisch Karin
Schramm Gabriele
Ballard Spahr Andrews & Ingersoll LLP
Bunner Bridget E
Forschungszentrum Borstel Zentrum fur Medizin und Biowissenschaf
Hamud Fozia M
LandOfFree
Immunomodulating agents from parasitic worms and method for... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Immunomodulating agents from parasitic worms and method for..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Immunomodulating agents from parasitic worms and method for... will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-4099498