Immunomodulating active substance

Details Immunomodulating active substance Immunomodulating active substance

1996-01-18

1998-03-24

Rotman, Alan L.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

C-o-group doai

5689095, A01N 3100, C07C 2900

Patent

active

057313571

ABSTRACT:
The invention is an immunomodulator-antistressant and allows to protect immune system from depressive influence of chronic emotional stress with this preventing depression in 1.25-2.5 times of immune reaction. It intensifies humoral immune reaction in 1.9-2.3 times and stimulates phagocyte activity of macrophages in 1.3-1.85 times which is especially important for treatment of immunodeficiency states.
With the presence of pathological increased immune reaction (autoimmune diseases--rheumatic arthritis, non-specific ulcerative colitis, psoriasis, chronic glomerulonephritis, etc.) it normalises it, suppressing the progress of humoral immune reaction in 4.7-11.8 times.

REFERENCES:
patent: 5073572 (1991-12-01), Gunasekera et al.
patent: 5280048 (1994-01-01), Yamamoto et al.
Hannus et al., Phytochemistry, 1974, vol. 13, pp. 2563-2566.
Roshehin et al., Rastitelnie Resursi, 1986, vol. 22, No. 4, pp. 530-537, English abstract.

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