Chemistry: analytical and immunological testing – Involving iga – igd – ige – or igm
Patent
1980-08-04
1983-03-08
Marantz, Sidney
Chemistry: analytical and immunological testing
Involving iga, igd, ige, or igm
435 7, 436548, 436529, 436540, G01N 3354, G01N 3356
Patent
active
043761100
ABSTRACT:
"Two-site" or "sandwich" immunometric assay techniques for determination of the presence and/or concentration of antigenic substances in fluids using monoclonal antibodies. One monoclonal antibody is presented in a soluble labeled form and a second monoclonal antibody is presented bound to a solid carrier; the soluble and bound monoclonal antibodies may be the products of either the same or different cell lines. Each monoclonal antibody has an affinity for the antigenic substances of at least about 10.sup.8 liters/mole.
REFERENCES:
patent: 3654090 (1972-04-01), Schuurs
patent: 3791932 (1974-02-01), Schuurs
patent: 3867517 (1975-02-01), Ling
patent: 4016043 (1977-04-01), Schuurs
patent: 4098876 (1978-07-01), Piasio
A. C. Cuello et al., Proc. Natl. Acad. Sci. U.S.A., vol. 76(7), 3532-3536 (Jul. 1979).
David Gary S.
Greene Howard E.
Hybritech Incorporated
Marantz Sidney
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