Immunologically active polypeptides with altered toxicity useful

Details Immunologically active polypeptides with altered toxicity useful Immunologically active polypeptides with altered toxicity useful

1995-06-07

1999-07-20

Mosher, Mary E.

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Recombinant dna technique included in method of making a...

4353201, 536 237, 4241901, 4242541, 424832, C12P 2102, C12N 1500

Patent

active

059255463

ABSTRACT:
Immunological active polypeptides with no or reduced toxicity useful for the preparation of an antipertussis vaccine. Method for the preparation of said polypeptides which comprises, cultivating a microorganism transformed with a hybrid plasmid including the gene/s which codes for at least one of said polypeptides in a suitable medium and recovering the desired polypeptide from the cells or from the culture medium.

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