Immunologically active polypeptides with altered toxicity...

Details Immunologically active polypeptides with altered toxicity... Immunologically active polypeptides with altered toxicity...

1994-06-17

2008-08-12

Mosher, Mary E (Department: 1648)

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Bacterium or component thereof or substance produced by said...

C530S350000

Reexamination Certificate

active

07410646

ABSTRACT:
Immunologically active polypeptides with no or reduced toxicity useful for the preparation of an antipertussis vaccine. Method for the preparation of said polypeptides which comprises, cultivating a microorganism transformed with a hybrid plasmid including the gene/s which codes for at least one of said polypeptides in a suitable medium and recovering the desired polypeptide from the cells or from the culture medium.

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