Immunologically active peptides capable of inducing immunization

Details Immunologically active peptides capable of inducing immunization Immunologically active peptides capable of inducing immunization

1984-06-26

1987-11-17

Phillips, Delbert R.

Drug, bio-affecting and body treating compositions

Lymphokine

530350, 530324, 530325, 530326, 530327, 530328, A61K 3702, C07K 1300, C07K 710, C07K 708, C07K 706

Patent

active

047073578

ABSTRACT:
An immunologically active substantially pure peptide capable of inducing in human an immune response which is cross reactive with and protective against infection by a malaria parasite, wherein the peptide contains at least 2 consecutive repeats of a sequence Asn-X-Y-Pro wherein X is Ala or Val and Y is Asn or Asp or a sequence of the formula Thr-Glu-Trp-Z-Pro-Cys-Ser-Val-Thr-Cys-Gly-Asn-Gly wherein Z is Ser or Thr or the formula Lys-Pro-S-T-S-Lys-Leu-Lys-Gln-Pro-U-V-Gly-W-Pro wherein S is Lys or Asn, T is His or Glu, U is Gly or Asn, V is As or Glu, and W is Asn or Gln is disclosed along with DNA sequences and various other genetic materials useful in producing these peptides through biological methods.

REFERENCES:
patent: 4466917 (1984-08-01), Nussenzweig et al.
patent: 4554101 (1985-11-01), Hopp
Science, vol. 220, (1983), 1285-1288.
Cell, vol. 34, 815-822, (1983).
Molecular and Biochem. Para. 15, (1985), 305-316.
J. Exp. Med., 157, (1983), 1947-1957.
The Journal of Biol. Chem., 258, No. 5, (1983), 3341-3345.
Biochem., (1984), 23, 5665-5670.
Molecular Parasitology, pp. 127-142, (1984).
Nature, vol. 305 (1983), 29-33.
Phil. Trans. R. Soc. Lond. B., 307, 129-139, (1984).

Affiliated with

Also associated with

Rating

Immunologically active peptides capable of inducing immunization does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Immunologically active peptides capable of inducing immunization, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Immunologically active peptides capable of inducing immunization will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-1449285