Drug – bio-affecting and body treating compositions – Radionuclide or intended radionuclide containing; adjuvant... – Molecular bilayer structure
Patent
1975-09-19
1979-04-10
Fagelson, Anna P.
Drug, bio-affecting and body treating compositions
Radionuclide or intended radionuclide containing; adjuvant...
Molecular bilayer structure
23230B, 1951035A, 210DIG23, 260112R, 260112B, 424 8, 424 11, 424 12, 424 13, 424177, G01N 2100, G01N 2300, G01N 3100, B01D 2101
Patent
active
041488695
ABSTRACT:
Immunological assaying methods which require insolubilization of an antigen-antibody complex as an integral step thereof are improved by adding to the test medium in which insolubilization is desired an aqueous reagent solution containing from about 3 to 6% by weight of a mixture of polyethylene glycol and a nonionic surfactant, and which solution has a calculated HLB (Hydrophilic-Lipophilic-Balance) of about 0.7 to 1.7. This solution increases the insolubilization of the antigen-antibody complex with reduced incubation times, and produces an assay procedure of greater test range and sensitivity. A preferred embodiment involves usage in a nephelometric analysis.
REFERENCES:
patent: 3489688 (1970-01-01), Pospischil
patent: 3492396 (1970-01-01), Dalton
patent: 3624197 (1971-11-01), Schain
patent: 3770380 (1973-11-01), Smith
patent: 3880989 (1975-04-01), Garcia
patent: 3897357 (1975-07-01), Carmello
Savory, Clin. Chem, vol. 20, No. 8, 1974, pp. 1071-1075.
Tiffany, Clin. Chem., vol. 20, No. 8, 1974, pp. 1055-1061.
Lizana, Clin. Chem., vol. 20, No. 4, 1974, pp. 415-420.
Hellsing, Protides of Biol. Fluids, Pergamon Press, Gt. Britain, vol. 21, 1974, pp. 579-583.
Creighton, J of Immunology, vol. III, 1973, pp. 1219-1227.
Harrington, Immunochem., vol. 8, 1971, pp. 413-421.
Lundkvist, Immunology, vol. 23, 1972, pp. 413-422.
Baxter Travenol Laboratories Inc.
Fagelson Anna P.
Flynn Lawrence W.
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