Immunological methods for removing species from the blood circul

Details Immunological methods for removing species from the blood circul Immunological methods for removing species from the blood circul

1977-01-21

1983-03-01

Spear, Jr., Frank A.

Liquid purification or separation

Processes

Liquid/liquid solvent or colloidal extraction or diffusing...

128214R, 210646, 210648, 2103213, 210927, B01D 3100, B01D 1300, A61M 103

Patent

active

043754147

ABSTRACT:
Immunoassays of psychoactive drugs including psychotomimetic drugs, narcotic drugs, and tetrahydrocannabinols and treatment methods based on the antigenic properties of protein conjugates of these drugs. These methods are based upon treating the psychoactive substances as haptens and utilizing their protein conjugates to produce antibodies to the psychoactive materials themselves. The immunoassay methods include both agglutination and agglutination-inhibition reactions. The treatment methods include treatment of both exogenous, administered drugs (such as cannabinols, LSD, heroin and morphine) and endogenous substances (such as N,N-Dimethyltryptamine and 5-Methoxy-N,N-Dimethyltryptamine, by active immunization and also passive immunization including immunodialysis and immunoadsorption treatment methods. Devices are disclosed for carrying out the immunodialysis and immunoadsorption methods.

REFERENCES:
patent: 3619423 (1971-11-01), Galletti et al.
patent: 3652761 (1972-03-01), Weetall
patent: 3734851 (1973-05-01), Matsumura
patent: 3742946 (1973-07-01), Grossman
patent: 3794584 (1974-02-01), Kuhin
patent: 3809613 (1974-05-01), Vieth et al.
patent: 3817837 (1974-06-01), Rubenstein et al.
Hyden, "An Extra-Corporeal Shunt Apparatus for Blood Detoxification", from Arzneim-Forsch (Drug Res.) Jahrgong 21, Nov. 1971, pp. 1671-1675.

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