Immunological method of measuring unstable analytes using cross-

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...

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436501, 436518, 436536, 436543, 436544, 436815, 436822, 436824, 436825, 435 79, 435961, G01N 33531, G01N 33532, G01N 3353, G01N 33543

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active

051282402

ABSTRACT:
A quantitative immunoassay for a beta-lactam antibiotic in a sample, which may contain open and closed ring forms of the antibiotic, is disclosed. Closed-ring forms of the antibiotic in the sample are converted to open-ring protein conjugates and detected through immunospecific reaction with antibodies raised against the open-ring protein conjugate form of the beta-lactam antibiotic.

REFERENCES:
patent: 4243749 (1981-01-01), Sadeh et al.
patent: 4288538 (1981-09-01), Groman et al.
patent: 4347312 (1982-08-01), Brown et al.
Isetta, A. et al., Eur. Journ. Immunol, 6: 737-742 (1976).

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