Immunological materials

Details Immunological materials Immunological materials

1976-01-14

1977-09-06

Gotts, Lewis

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

424 55, 260112B, 260112R, 260121, C08L 8900

Patent

active

040467228

ABSTRACT:
The present invention is concerned with a cytotoxic agent comprising an immunoglobulin specific for antigens on the surface of the cell to be killed having 1-10 polymer carrier molecules covalently bonded thereto and the polymer carrier having 5-500 molecules of a cytotoxic drug covalently bound. The compounds of the present invention are useful as anti tumor agents.

REFERENCES:
sela et al., "Studies on . . . of Proteins", Biochem. Journal, 1962, vol. 85, pp. 223-235.

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