Immunological lipid emulsion adjuvant

Details Immunological lipid emulsion adjuvant Immunological lipid emulsion adjuvant

1986-04-15

1989-02-21

Thexton, Matthew A.

Drug, bio-affecting and body treating compositions

Whole live micro-organism, cell, or virus containing

Genetically modified micro-organism, cell, or virus

424 89, 424 88, 514 21, 514885, 514937, A61K 3900

Patent

active

048063525

ABSTRACT:
An immunological adjuvant is provided which enhances the immune response against antigens, and accordingly is useful in vaccines. The adjuvant system is comprised of (1) a lipid emulsion system containing a metabolizable oil, a low molecular weight polyol and lecithin and (2) at least one refined detoxified bacterial biological adjuvant.

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Reynolds et al., "Infection and Immunity", vol. 28, No. 3, pp. 937-943: 1980.
American Journal of Veterinary Research, vol. 44, No. 1, pp. 72-75: 1983.
B. E. Straw et al., Can J. Comp. Med.: 1985; 49, pp. 149-151.
M. Brugh et al., American Journal of Veterinary Research, vol. 44, No. 1: 1983.

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