Immunological diagnostic reagents comprising thio-amine terminat

Details Immunological diagnostic reagents comprising thio-amine terminat Immunological diagnostic reagents comprising thio-amine terminat

1978-07-31

1980-10-07

Woodberry, Edward M.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

260 6, 260 297DP, 424 12, 424 79, 424 81, 435180, 435181, 435182, 525291, A61K 3900, C08L 2500, C08L 8900, G01N 3100

Patent

active

042267471

ABSTRACT:
A reagent for an immunological determination comprising water insoluble latex particles being formed from vinyl polymerizates and having free terminal functional groups of the formula: ##STR1## through which are bound an immunologically active material including materials for preparing this reagent and for utilizing this reagent for diagnostic purposes. The latex particles contain a core and an outer layer, said core being formed by polymerization of vinyl, or diene monomers or mixtures thereof with said polymerizates in said core carrying a functional group selected from group consisting of carboxyl, sulfonate or mixtures thereof and said outer layer being formed from vinyl polymerizates carrying said terminal functional group.

REFERENCES:
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patent: 4059685 (1977-11-01), Johnson
patent: 4064080 (1977-12-01), Daniel
patent: 4118349 (1978-10-01), Bonacker et al.
patent: 4134872 (1979-01-01), Lee
patent: 4140662 (1979-02-01), Reckel et al.
patent: 4156669 (1979-05-01), Lee
Chem. Absts., vol. 87:64403n, Carrier with side chains for fixing organic compounds with a glucide residue, Quash.
Chem. Absts. vol. 71:79250d, Protein-containing reagents, Adams et al.
Chem. Absts. vol. 77:137144j, Detecting Antigens or Anti-bodies in a body fluid, Cleeland et al.

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