Immunological complex comprising an antigen of Simian Immunodefi

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving virus or bacteriophage

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435 71, 435 79, 435 792, 435974, 436536, 424 89, C12Q 170

Patent

active

052682650

ABSTRACT:
The invention relates to a new variety of retroviruses designated Immunodeficiency Virus Type II, HIV-II, samples of which have been deposited at CNCM as I-502 and I-532. It also concerns purified forms of the antigens which can be obtained from this virus, in particular from the gp 36 and gp 130-140 proteins. These various antigens are useful in medical diagnosis and kits, in particular by being placed in contact with serum of the patient to be diagnosed. Lastly, the invention relates to immunizing compositions, in particular containing at least one of glycoproteins gp 36 and gp 130-140.

REFERENCES:
patent: 4708818 (1987-11-01), Montagnier et al.
patent: 4839288 (1989-06-01), Montagnier et al.
Kauki et al., "Serologic Identification and Characterization of a Macaque T-Lymphotropic Retrovirus Closely Related to HTLV-III", Science, 228 (1985) 1199-1201.
Daniel et al., "Isolation of T-Cell Tropic HTLV-III-Like Retrovirus from Macaques" Science 228 (1985) 1201-1204.

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