Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Fusion protein or fusion polypeptide
Reexamination Certificate
2006-01-10
2006-01-10
Graser, Jennifer E. (Department: 1645)
Drug, bio-affecting and body treating compositions
Antigen, epitope, or other immunospecific immunoeffector
Fusion protein or fusion polypeptide
C424S234100, C424S192100, C424S193100, C424S197110, C424S200100, C424S201100, C424S203100, C424S237100, C424S244100, C530S350000, C435S069100, C435S069300, C435S069700, C435S071100
Reexamination Certificate
active
06984385
ABSTRACT:
Immunological compositions and methods for making and using them. The compositions contain at least one antigen and at least one lipoprotein and optionally an adjuvant. The lipoprotein can itself be antigenic or immunogenic. The antigen can be influenza HA and the lipoprotein a recombinantly expressed product having an OspA leader for lipidation and PspA for the protein portion. The antigen can be OspC and the lipoprotein OspA. The components of the composition are co-administered. A potentiated immunological response is obtained by the compositions and methods.
REFERENCES:
patent: 93/07897 (1993-04-01), None
Becker Robert S.
Biscardi Karen S.
Erdile Lorne F.
Gray Maryann
Guy Bruno
Connaught Laboratories Inc.
Graser Jennifer E.
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