Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Carbohydrate doai
Reexamination Certificate
2005-03-01
2005-03-01
Wilson, James O. (Department: 1623)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Carbohydrate doai
C514S025000, C536S004100, C536S005000, C536S006100, C424S184100
Reexamination Certificate
active
06861410
ABSTRACT:
The present invention is directed to novel adjuvant compositions, which target the cellular and/or humoral arms of immunity. According to an embodiment of the invention, an oil-in-water adjuvant composition is provided that comprises: (a) water; (b) a metabolizable oil comprising at least one branched or unbranched long-chain hydrocarbon moiety; (c) a steroid; and (d) a saponin.
REFERENCES:
patent: 4806350 (1989-02-01), Gerber
patent: 4900549 (1990-02-01), De Vries et al.
patent: 5118671 (1992-06-01), Bombardelli et al.
patent: 5688772 (1997-11-01), Estrada et al.
patent: 5880103 (1999-03-01), Urban et al.
patent: 5914113 (1999-06-01), Schrier
patent: 5976604 (1999-11-01), Kunieda et al.
patent: 6080725 (2000-06-01), Marciani
patent: 6086901 (2000-07-01), O'Hagan et al.
patent: 6299884 (2001-10-01), Van Nest et al.
patent: 6306405 (2001-10-01), O'Hagan et al.
patent: 6342224 (2002-01-01), Bruck et al.
patent: 6372227 (2002-04-01), Garcon et al.
patent: 0 822 831 (1996-01-01), None
patent: WO 9003184 (1990-04-01), None
patent: WO 9857659 (1998-12-01), None
patent: WO 9912565 (1999-03-01), None
patent: WO 0043511 (2000-07-01), None
Bomford et al., “Adjuvanticity and ISCOM Formation by Structurally Diverse Saponins”, 1992, Vaccine, 10(9):572-577.
Guy et al., “Design, Characterization and Preclinical Efficacy of a Cationic Lipid Adjuvant for Influenza Split Vaccine”, 2001, Vaccine, 19:1794-1805.
Sanchez et al., “Formulations of Single of Multiple H. Pylori Antigens with DC Chol Adjuvant Induce Protection by the Systemic Route in Mice Optimal Prophylactic Combinations are Different from Therapeutic Ones”, 2001, FEMS Immunology and Medical Microbiology, 30:157-165.
Singh et al., “Advances in Vaccine Adjuvants”, 1999, Nature Biotechnology, 17(11):1075-1081.
Sjolander et al., “Uptake and Adjuvant Activity of Orally Delivered Saponin and ISCOM™ Vaccines” 1998, Adv. Drug Delivery Rev., 34:321-338.
Mowat et al., “ISCOMS—A Novel Strategy for Mucosal Immunization?” 1991, Immunology Today, 12:383-385.
Takahashi et al., “Induction of CD8 Cytotoxic T Cells by Immunization with Purified HIV-1 Envelope Protein in ISCOMs”, 1990, Nature, 344:873-875.
O'Hagan Derek
Ott Gary S.
Singh Manmohan
Blackburn Robert P.
Bonham David B.
Chiron Corporation
McIntosh III Traviss C.
Moran Michael J.
LandOfFree
Immunological adjuvant compositions does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Immunological adjuvant compositions, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Immunological adjuvant compositions will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-3366878