Immunological adjuvant and process for preparing the same, pharm

Details Immunological adjuvant and process for preparing the same, pharm Immunological adjuvant and process for preparing the same, pharm

1986-09-02

1989-10-31

Rollins, John W.

Drug, bio-affecting and body treating compositions

Whole live micro-organism, cell, or virus containing

Genetically modified micro-organism, cell, or virus

514885, 514938, 514942, A61K 3902

Patent

active

048776122

ABSTRACT:
A process is provided for preparing immunological adjuvants (which are unusual in that they do not contain mycolic acids, mycolic acid esters or lipopolysaccharides, and can increase the immune response in animals of soluble and particulate antigens without the presence of oil or oily vehicles, and without inducing adjuvant arthritis or other undesirable side effects) by solvent extraction from a species of Amycolata, a genus of filamentous branching bacteria known as Amycolata, as well as pharmaceutical compositions containing such adjuvants, and a process for increasing the immune response of antigens in animals by administration of such adjuvants.

REFERENCES:
patent: 4010257 (1977-03-01), Adlam et al.
Chem. Abst., 84:111,636r, 1976.

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