Immunologic enhancement of the somatogenic effect of somatotropi

Details Immunologic enhancement of the somatogenic effect of somatotropi Immunologic enhancement of the somatogenic effect of somatotropi

1990-05-15

2000-12-26

Swart, Rodney P.

Drug, bio-affecting and body treating compositions

Immunoglobulin, antiserum, antibody, or antibody fragment,...

Monoclonal antibody or fragment thereof

4241391, 4241411, 436513, 436536, 530386, 5303871, 5303881, 53038824, A61K 39395, G01N 33563, C07K 100, C12P 2108

Patent

active

061654655

ABSTRACT:
The present invention is directed to antibodies, in particular monoclonal antibodies, of porcine somatotropin (pST). When these antibodies are administered together with pST, the growth of vertebrates is greater than that achieved with the administration of pST alone. The invention is also directed to an increase in the growth of vertebrates which persists over long periods when an antibody to a somatotropin is administered together with such somatotropin.

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patent: 4925922 (1990-05-01), Byers et al.
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Ferrara, P., et al., European J. Immunology, 9, 1020-1023 (1979).
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Retegui, L.A., et al., Endocrinology, 111, 668-676 (1982).
Hughes, J.P., and Friesen, H.G., Ann. Rev. Physiol., 47, 469-482 (1985).
Arthur C. Guyton, M.D., Textbook of Medical Physiology, Pub. W.B.Saunders Co., 1981, pp. 919-923.

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