Immunologic detection of factor V(VA) fragments in hemorrhagic a

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...

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422 61, 436548, 530381, C12Q 100, C07K 1506, G01N 3353

Patent

active

050494910

ABSTRACT:
The present invention is directed to immunochemical detection procedures, e.g., using both Western blotting and direct immunoassays, for Factor V/Va and Factor V/Va fragments, which can thus be used; (a) in a predictive manner to evaluate the existence and/or extent of a thrombotic complication; (b) to monitor the efficacy of prophylaxis for a thrombotic condition; and (c) as a means to evaluate potential risk of hemorrhage during thrombolytic therapy.

REFERENCES:
Ratnoff, "Thrombosis and the hypercoagulable state", Embase No. 85002264, dialog acc. no. 5756754, 1984.

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