Drug – bio-affecting and body treating compositions – Conjugate or complex of monoclonal or polyclonal antibody,... – Conjugated via claimed linking group – bond – chelating agent,...
Patent
1979-07-31
1981-03-31
Brown, Johnnie R.
Drug, bio-affecting and body treating compositions
Conjugate or complex of monoclonal or polyclonal antibody,...
Conjugated via claimed linking group, bond, chelating agent,...
424182, 536 4, 536 5, 536121, A61K 3170, A61K 31705, C07H 510
Patent
active
042593247
ABSTRACT:
Compounds of the formulae Y--R wherein Y is 1-thio-.beta.-L-fucose, 1-thio-.beta.-D-galactose or 1-thio-.beta.-lactose and R is 2-(1-adamantyl)ethyl, 3-[(p-tetrafluorophenethyl)phenyl]propyl, 6-(5-cholesten-3.beta.-yloxy)hex-3-ynl, oleyl, or hexadecyl are useful immunologic adjuvants in vaccines.
REFERENCES:
patent: 4189471 (1980-02-01), Ponpipom et al.
Behling et al., "Jour. of Immunology", vol. 117, No. 3, Sep. 1976, pp. 847-851.
Bugianesi Robert L.
Ponpipom Mitree M.
Shen Tsung-Ying
Brown Johnnie R.
Levitt Julian S.
Merck & Co. , Inc.
Perrella Donald J.
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