Immunoglobulin E receptor .alpha.-chain inhibits IgE production

Details Immunoglobulin E receptor .alpha.-chain inhibits IgE production Immunoglobulin E receptor .alpha.-chain inhibits IgE production

1994-05-03

1999-02-23

Crouch, Deborah

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Peptide containing doai

514885, A61K 3800

Patent

active

058744045

ABSTRACT:
Disclosed is an antiallergic composition comprising, as an active ingredient, a peptide which is capable of binding to human IgE, more specifically the high-affinity immunoglobulin E receptor .alpha.-chain or a soluble fragment, which is capable of binding to human IgE, or the high-affinity immunoglobulin E receptor .alpha.-chain. The composition is clinically useful for blocking allergic responses. An animal model for use in the screening of prophylactic and therapeutic compositions for IgE-related diseases is also disclosed.

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