Immunoglobulin display vectors

Details Immunoglobulin display vectors Immunoglobulin display vectors

2011-05-24

2011-05-24

Qian, Celine X (Department: 1636)

Chemistry: molecular biology and microbiology

Vector, per se

C435S325000

Reexamination Certificate

active

07947495

ABSTRACT:
Disclosed are mammalian expression vectors for expressing simultaneous expression of immunoglobulins as both a secreted and cell surface bound form.

REFERENCES:
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Brezinsky et al., “A simple method for enriching populations of transfected CHO cells for cells of higher specific productivity,” Journal of Immunological Methods, Elsevier Science Publishers B.V., Amsterdam, NL vol. 277, No. 1-2. Jun. 1, 2003, pp. 141-155.
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Li et al., A Comparative study of different vector designs for the mammalian expression of recombinant IgG antibodies, Journal of Immunological Methods, Elsevier Science Publishers B,V., Amsterdam, NL, vol. 318, No. 1-2, Jan. 3, 2007, pp. 113-124.
International Search Report and Written Opinion for PCT/US2008/082131, dated Sep. 29, 2009.

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