Immunoglobulin and fiber-containing composition for human gastro

Details Immunoglobulin and fiber-containing composition for human gastro Immunoglobulin and fiber-containing composition for human gastro

1995-05-09

1996-07-02

Nutter, Nathan M.

Drug, bio-affecting and body treating compositions

Whole live micro-organism, cell, or virus containing

Bacteria or actinomycetales

424 9345, 4241301, 4241431, 4241451, 4241471, 4241481, 4241491, 4241501, 4241511, 4241571, 4241581, 4241591, 4241611, 4241951, 4242341, 424499, 424500, 424535, 424809, 514 2, 514439, 514441, 514445, 514777, 514867, A01N 6304, A61K 3902, A61K 39395, A61K 3940

Patent

active

055319890

ABSTRACT:
A composition for restoring and maintaining gastrointestinal health comprises 40-60% by weight of an immunoglobulin composition comprising concentrated immunologically active immunoglobulins and 40-60% by weight of soluble dietary fiber selected from inulin, fructo-oligosaccharides, pectin, guar gum, and mixtures thereof. The immunoglobulin and fiber-containing composition can optionally contain one or more of a beneficial human intestinal microorganism, components of a non-immune natural defense system, an iron-sequestering molecule, and gluconic acid. Preferred beneficial human intestinal microorganisms include lactobacilli and bifidobacteria. The immunologically active immunoglobulins are preferably purified from bovine milk, milk products, or whey. Methods of use are also described.

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Gilliland et al "Antagonistic Action of Lactobacillus acidephilus Toward Intestinal and Foodborne Pathogens in Associative Cultures", Dec. 1977 J. of Food Prot. vol. 40, No. 12 pp. 820-823.
Hilpert et al, J. of Infectious Diseases, vol. 156, No. 1, Jul. 1987 pp. 158-166.
Gilliland et al, J. Dairy Sci. 73:905-911, 1990.
Tacket et al, N.E.J. of Medicine, May 12, 1988, vol. 318, No. 19 pp. 1240-1243.
Cunningham-Rundles et al, J. of Clin. Imm. vol. 6, No. 5, 1986, p. 381-388.

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