Immunogens for meningitidis-A vaccines

Details Immunogens for meningitidis-A vaccines Immunogens for meningitidis-A vaccines

2006-05-08

2011-11-22

Navarro, Albert (Department: 1645)

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

C424S193100, C424S194100, C424S197110, C424S234100

Reexamination Certificate

active

08062641

ABSTRACT:
An oligosaccharide useful for a Meningitidis A vaccine contains a first mannose unit having a spacer in the alpha configuration at C-1, which spacer is capable of conjugating to a protein, and which is connected to a second mannose unit through a 1,6-linkage which connects C-6 of the first unit to C-1 of the second unit, wherein the 1,6-linkage comprises a phosphonate. Related methods of making such compounds, analogous compounds, or intermediates thereof are also disclosed.

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Written Opinion of the International Searching Authority for PCT/IB2006/001703, mailed on May 8, 2007, 11 pages.

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