Immunogenicity of glucan binding protein

Details Immunogenicity of glucan binding protein Immunogenicity of glucan binding protein

2008-01-29

2008-01-29

Swartz, Rodney P (Department: 1645)

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Amino acid sequence disclosed in whole or in part; or...

C424S009100, C424S009200, C424S184100, C424S185100, C424S193100, C424S197110, C424S203100, C424S234100, C424S244100, C435S069100, C435S183000, C435S193000, C435S253400, C530S300000, C530S350000

Reexamination Certificate

active

10383930

ABSTRACT:
Immunogenic compositions and subunit vaccines for dental caries are described which comprise peptide subunits of glucan binding protein-B and peptide subunits of glucan binding protein-B in combination with peptide subunits of glucosyltransferase. Methods of provoking an immune response toS. mutansglucan binding protein-B or glucosyltransferase. Methods of immunizing a mammal against dental caries are also described, along with antibodies which bind particular epitopes of glucan binding protein-B or glucosyltransferase.

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