Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving virus or bacteriophage
Reexamination Certificate
2007-07-24
2010-06-22
Mosher, Mary E (Department: 1648)
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving virus or bacteriophage
C435S007100, C502S004000, C502S007000
Reexamination Certificate
active
07741024
ABSTRACT:
An immunogenic proteoliposome containing a transmembrane protein or oligomeric complexes containing such proteins, including viral envelope glycoproteins, in a lipid membrane around an elliptoid or spherical shape. The shape preferably also contains an attractant such as streptavidin or avidin and the lipid membrane contains a moiety that binds to the attractant such as biotin. The immunogenic transmembrane protein is bound to a ligand which is anchored in the shape. Methods for making the immunogenic proteoliposomes are provided. uses of the proteoliposome are described, including their use as immunogens to elicit immune reaction, and their use in screening assays, including their use as antigens to screen antibody libraries, as well as for drug screening and the identification of ligands.
REFERENCES:
patent: 5766625 (1998-06-01), Schreier et al.
patent: 5817316 (1998-10-01), Sodroski
patent: 5858366 (1999-01-01), Sodroski
patent: 6761902 (2004-07-01), Sodroski et al.
patent: WO 99/16883 (1999-04-01), None
patent: WO 01/19958 (2001-03-01), None
patent: WO 01/49265 (2001-07-01), None
Alkhatib, G., et al., Science 272:1955-1958 (1996).
Allan, JS., et al., Science 228:1091-1093 (1985).
Barré-Sinoussi, F., et al., Science 220:868-871 (1983).
Berman, PW., et al., J. Infect. Dis. 176:384-97 (1997).
Broder, C.C., et al., Proc. Natl. acad. Sci USA 91:11699-703 (1994).
Bullough, P., et al., Nature 371:37-43 (1994).
Burton, D. R. and D. C. Montefiori, AIDS 11 Suppl. A: S87-98 (1997).
Burton, D. R. and J. P. Moore, Nature Med. 4 (5 Suppl.) 495-8 (1998).
Cao, J., et al., J. Virol. 67:2747-55 (1993).
Carr, CM., et al., Cell 73:823-832 (1993).
Chan, DC., et al., Cell 89:263-273 (1997).
Choe, H., et al., Cell 85:1135-1148 (1996).
Choe, H., et al., Semin. Immunol. 10:249-57 (1998).
Connor, R. I., et al., J. Virol. 72:1552-76 (1998).
Dalgleish, AG., et al., Nature 312:763-767 (1984).
Deng, HK., et al., Nature 381:661-666 (1996).
Doranz, BJ., et al., Cell 85:1149-1158 (1996).
Dragic, T., et al., Nature 381:667-673 (1996).
Earl, PL., et al., J. Virol. 65:2047-2055 (1991).
Farzan, M., et al., J. Virol. 72:7620-5 (1998).
Fauci, A. S., et al., Ann Intern Med 100: 92-106 (1984).
Federsppiel et al., Genomics 16:707-712, 1993.
Feng, Y., et al., Science 272:872-877 (1996).
Freed, E.O., et al., Proc. Natl. Acad. Sci. USA 87:4650-4 (1990).
Gallo, RC., et al., Science 224:500-503 (1984).
Helseth, E., et al., J. Virol. 65:2119-23 (1991).
Helseth, E., et al., J. Virol. 64:6314-8 (1990).
Hill, C. P., et al., Proc. Natl. Acad. Sci. USA 93:3099-3104 (1996).
Jazin et al., Regulatory Peptides 47:247-258, 1993.
Klatzmann, D., et al., Nature 312:767-8 (1984).
Kowalski, M., et al., Science 237:1351-1355 (1987).
Loetscher et al., J Bio Chem 269(1):232-237, 1994.
Mascola, J. R., et al., J. Infect. Dis. 173:340-8 (1996).
McDougal, J. S., et al., J. Immunol. 137:2937-44 (1986).
McKeating, J. A., et al., J. Virol. 65:852-60 (1991).
Mirzabekov et al., J. Biol. Chem., 274:28745-50 (1999).
Montefiori, D. C. and Evans, T. G., AIDS Res. Human Retroviruses 15:689-98 (1999).
Moore, J. P. et al., J. Virol. 69:101-109 (1995).
Moore, J. P. and Sodroski, J., J. Virol. 70:1863-1872 (1996).
Moore, J. P., et al., J. Virol. 68:469-484 (1994).
Parren, P. W. H. I. and Burton, D. R., Nature Med. 3:366-7 (1997).
Parren, P. W. H. I., et al., J. Virol. 72: 3512-9 (1998).
Rao, Z., et al., Nature 378:743-7 (1995).
Robey, WG., et al., Science 228:593-595 (1985).
Tan, K., et al., Proc. Natl. Acad. Sci. USA 94:12303-8 (1997).
Veronese, F. D., et al., Science 229:1402-1405 (1985).
Wyatt, R., et al., J. Virol. 71:9722-31 (1997).
Wyatt, R., and J. Sodroski, Science 280:1884-8 (1998).
Grundner, C. et al., J Virol. 76(7):3511-3521, 2002.
Grundner, C. et al., Virology 331(1):33-46, 2005.
Moulard, M. et al., J Virol. 74(4):1948-1960, 2000.
Yang, X. et al., J Virol. 76(9):4634-4642, 2002.
Yang, X. et al., J Virol. 75(3):1165-1171, 2001.
Yang, X. et al., J Virol. 74(10):4746-4754, 2000.
Yang, X. et al., J Virol. 74(12):5716-5725, 2000.
Weissenhorn, W., et al., Nature 387:426-430 (1997).
Weissenhorn, W., et al., Proc. Natl. Acad. Sci. USA 95:6032-6 (1998).
Weissenhorn, W., et al., Mol. Cell 2:605-16 (1998).
Willey et al., J. Virol. 68:1029-39 (1994).
Grundner Christoph
Mirzabekov Tajib
Sodroski Joseph G
Wyatt Richard T
Dana-Farber Cancer Institute Inc.
Fish & Richardson P.C.
Hill Myron G
Mosher Mary E
LandOfFree
Immunogenic proteoliposomes, and uses thereof does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Immunogenic proteoliposomes, and uses thereof, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Immunogenic proteoliposomes, and uses thereof will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-4161996