Immunogenic proteins of Leptospira

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...

Reexamination Certificate

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C435S007100, C435S007200, C435S007220, C435S007900, C435S007500, C435S007920, C435S028000, C530S300000, C530S350000, C424S234100, C424S269100

Reexamination Certificate

active

07655427

ABSTRACT:
The invention provides novel immunogenic proteins LigA and LigB fromLeptospirafor use in the development of effective vaccines and antibodies, as well as improved diagnostic methods and kits.

REFERENCES:
patent: 2004/0058323 (2004-03-01), Ko et al.
patent: 2003/098214 (2003-11-01), None
Jusuf, S. S., et al., “Leptospira interrogansSurface Protein LK90 (LK90) gene, complete cds”,GenEmbl Database, Accession No. U95056,(1997),3 p.
Jusuf, S. S., et al., “Surface Protein Lk90”,GenEmbl Database, Accession No. O05734,(1997),2 p.
Palaniappan, R. U., et al., “Cloning and Characterization of a LigB Protein ofLeptospira interrogans”, GenEmbl Database, Accession No. Q7X2A1,(2002),3 p.
Palaniappan, R. U., et al., “Cloning and Molecular Characterization of an Immunogenic LigA Protein ofLeptospira interrogans”, Infection and Immunity, 70, Obtained from http://iai.asm.org,(2002),5924-5930.
Palaniappan, R. U., et al., “Leptospira interrogansSerovar Pomona Immunoglobulins-like B Protein Gene, Complete cds”,GemEmbl Database, Accession No. AF534640,(2002),5 p.
Ren, S. X., et al., “Leptospira interrogansSerovar Lai Str. 56601 Chromosomes I, Section 342 of 397 of the complete sequence”,GenEmbl Database, Accession No. ae011533,(2002),2 p.
Ren, S. X., et al., “Surface Protein LK90-like Protein”,GenEmbl Database, Accession Nos. Q8EZS3 & Q8F124,(2002),4 p.

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