Immunogenic polypeptide and method for purifying it

Details Immunogenic polypeptide and method for purifying it Immunogenic polypeptide and method for purifying it

1988-03-30

1992-12-15

Richter, Johann

Chemistry: natural resins or derivatives; peptides or proteins;

Proteins, i.e., more than 100 amino acid residues

530416, 424 88, C07K 300, C07K 1300

Patent

active

051718430

ABSTRACT:
This invention relates to a synthetic polypeptide (preferably produced by recombinant DNA techniques) comprising an amino acid sequence incorporating (a) a portion of the P.vivax circumsporozoite (CS) protein including the region of the repeat immunodominant epitope of said protein and (b) another portion of such protein which is conserved among the different material species; and to a method for purifying such a polypeptide.

REFERENCES:
Dame et al, Science, 225(4662), 593-599, 1983.

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