Chemistry: natural resins or derivatives; peptides or proteins; – Peptides of 3 to 100 amino acid residues – 15 to 23 amino acid residues in defined sequence
Patent
1985-10-02
1988-09-20
Kight, John
Chemistry: natural resins or derivatives; peptides or proteins;
Peptides of 3 to 100 amino acid residues
15 to 23 amino acid residues in defined sequence
530300, 530351, 530806, 530810, 530812, 530402, 530403, 530405, 514 2, 514 13, 514885, C07K 710
Patent
active
047726857
ABSTRACT:
Several distinct peptide regions of the secreted form of purified human interleukin-1 species pI 6.8 have been found to exhibit characteristics associated with highly immunogenic protein moieties and are used to produce specific anti-peptide antibodies. The antibodies raised against the individual peptides are specific for the peptide used for their production and for IL-1, pI 6.8. The individual antibodies bind to both the precursor of IL-1, pI 6.8 and the mature or extracellular IL-1, pI 6.8.
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Bayne Ellen B. K.
Boger Joshua S.
Schmidt John A.
Draper Garnette D.
Kight John
Merck & Co. , Inc.
Perrella Donald J.
Pfeiffer Hesna J.
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