Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Amino acid sequence disclosed in whole or in part; or...
Patent
1993-10-12
1999-01-12
Smith, Lynette F.
Drug, bio-affecting and body treating compositions
Antigen, epitope, or other immunospecific immunoeffector
Amino acid sequence disclosed in whole or in part; or...
4241841, 4242041, 4242081, 530324, 530350, 530331, 935 11, A61K 3921, A61K 3912, A61K 500, C07K 700
Patent
active
058583661
ABSTRACT:
Immunogenic peptides containing amino acid residues which define a binding site to a CD4 receptor are disclosed. Antibodies to these peptides are also disclosed. Methods of reducing the ability of a gp12O env protein to bind to CD4 are also disclosed. Methods of treatment and prophylaxis using these antibodies and peptides are also described.
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Furman Craig D.
Haseltine William A.
Helseth Eirik
Olshevsky Udy
Sodroski Joseph G.
Conlin David G.
Dana-Farber Cancer Institute
Eisenstein Ronald I.
Smith Lynette F.
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