Immunogenic Hepatitis C virus non-structural polypeptides

Details Immunogenic Hepatitis C virus non-structural polypeptides Immunogenic Hepatitis C virus non-structural polypeptides

2006-01-17

2006-01-17

Housel, James (Department: 1648)

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Virus or component thereof

C424S185100, C424S186100, C424S189100, C424S204100, C530S300000, C530S350000

Reexamination Certificate

active

06986892

ABSTRACT:
Polypeptides comprising a mutant non-structural Hepatitis C virus useful in diagnostic and/or immunogenic compositions are disclosed, in which the mutant is an N-terminal mutation that functionally disrupt the catalytic domain of NS3. Polynucleotides encoding these polypeptides, host cells transformed with polynucleotides and methods of using the polypeptides and polynucleotides are also disclosed.

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