Immunogenic glycopeptides, screening, preparation and uses

Details Immunogenic glycopeptides, screening, preparation and uses Immunogenic glycopeptides, screening, preparation and uses

2004-09-30

2010-10-26

Jones, D L (Department: 1618)

Drug, bio-affecting and body treating compositions

In vivo diagnosis or in vivo testing

C424S009200, C424S184100, C424S234100, C424S248100

Reexamination Certificate

active

07820142

ABSTRACT:
The invention relates to immunogenic glycopeptides derived from pathogenic microorganisms, which can be used for immunization and diagnosing infections dye to such pathogenic microorganisms and also to method for the selection and preparation thereof.

REFERENCES:
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U.S. Appl. No. 12/034,926, filed Feb. 21, 2008, Marchal, et al.
U.S. Appl. No. 11/576,203, filed Mar. 28, 2007, Marchal et al.
Karen M. Dobos, et al., “Definition of the Full Extent of Glycosylation of the 45-Kilodalton Glycoprotein ofMycobacterium tuberculosis” Journal of Bacteriology, May 1996, pp. 2498-2506.
Henrikl Franzyk, et al., “Synthesis of aliphaticO-dimannosyl amino acid building blocks for solid-phase assembly of glycopeptide libraries”, J. Chem. Soc. Perkin Trans.1, (1995), pp. 2883-2898.
Felix Romain, et al., “Deglycosylation of the 45/47-Kilodalton Antigen Complex ofMycobacterium tuberculosisDecreases Its Capacity to Elicit in Vivo or in Vitro Cellular Immune Responses”, Infection and Immunity, Nov. 1999, pp. 5567-5572, vol. 67, No. 11.

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