Immunogenic formulation and process for preparation thereof

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...

Reexamination Certificate

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C435S006120, C435S005000, C435S004000, C435S091500, C424S189100, C424S187100, C424S193100, C424S278100, C530S350000, C530S300000, C514S002600

Reexamination Certificate

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07118874

ABSTRACT:
A process is disclosed for preparation of a immunogenic peptide mixture in a single synthesis. The peptide mixture collectively represents the in vivo variability seen in immunogenic epitopes from a pathogen. The mixture is termed a hypervariable epitope construct (HEC). Immunization with a HEC evokes broadly reactive immunity against divergent strains of a pathogen upon which the HEC is based.

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