Immunogenic E. coli ST enterotoxin derivatives and compositions

Details Immunogenic E. coli ST enterotoxin derivatives and compositions Immunogenic E. coli ST enterotoxin derivatives and compositions

1980-04-04

1982-02-09

Hazel, Blondel

Drug, bio-affecting and body treating compositions

Whole live micro-organism, cell, or virus containing

Genetically modified micro-organism, cell, or virus

424177, 424 88, 260112R, A61K 39108, A61K 3902, C07G 700

Patent

active

043149936

ABSTRACT:
E. coli heat stable (ST) enterotoxin derivatives are prepared by reaction of E. coli ST enterotoxin with crosslinking agents for proteins. The so-obtained crosslinked ST enterotoxins show immunogenic activity; they are valuable prophylactic agent for protecting man and animals against diarrheal disease provoked by E. coli enterotoxin and they may be formulated into compositions for intramuscular, subcutaneous or oral administration.

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