Immunogenic compositions comprising glycosylated and deglycosyla

Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Virus or component thereof

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4241881, 530350, A61K 3921

Patent

active

060569638

ABSTRACT:
This invention is directed to a composition comprising one or more human immunodeficiency virus type 2 (HIV-2) envelope proteins and a pharmaceutically acceptable carrier. The proteins of the claimed invention are gp300, p200 and p90/80 of HIV-2. The composition is useful for the diagnostic assay of HIV-2 and as an antigen for the production of antibodies, for example.

REFERENCES:
patent: 4839288 (1989-06-01), Montagnier et al.
Veronese, "Indentification of Simian Immunodeficiency Virus SIV MAC env Gene Products", Journal of Virology, 1416-1419, 1989.
Graham et al., 1995, New Engl. J. Med. 333:1331-1339.
Haynes, B., 1993, Science 260:1279-1286.

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