Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Amino acid sequence disclosed in whole or in part; or...
Patent
1994-11-18
1998-01-13
Mosher, Mary E.
Drug, bio-affecting and body treating compositions
Antigen, epitope, or other immunospecific immunoeffector
Amino acid sequence disclosed in whole or in part; or...
530324, 530325, 530326, 530350, 4242291, 930220, A61K 3927, A61K 3800, C07K 708, C07K 1403
Patent
active
057076294
ABSTRACT:
The present invention is directed to a gene encoding an envelope glycoprotein of equine herpesvirus type 1 (EHV-1), the glycoprotein D (gD) gene, its gene product and antibodies directed against gD polypeptides. The envelope glycoproteins of herpesvirus are major targets of the immune response to herpesviral infection. Hence, an important aspect of this invention is directed towards a vaccine against EHV-1 and treatment of EHV-1 infection by anti-EHV-gD antibodies or antisera.
REFERENCES:
Allen et al. J. Virology 61:2454-2461, 1987.
Whittaker et al. J. General Virology 73:801-809, 1992.
Stokes, et al. (1989), "A Hamster Model of Equine Herpesvirus Type I (EHV-1) Infection; Passive Protection by Monoclonal Antibodies to EHV-1 Glycoproteins 13, 14 and 17/18," J. Gen. Virol. 70: 1173-83.
Guo, et al. (1990), "Coexpression by Vaccinia Virus Recombinants of Equine Herpesvirus I Glycoproteins gp13 and gp14 Results in Potentiated Immunity", J. Virol. 64: 2399-2406.
Shimizu, et al., (1989), "Monoclonal Antibodies with Neutralizing Activity to Equine Herpesvirus I," Arch. Virol. 104: 169-74.
Paoletti (1990), "Herpes Virus Recombinant Poxvirus Vaccine," Chem Abstracts 115(3): Abstract 23680d.
Audonnet, et al., (1990) "Equine Herpesvirus Type I Unique Short Fragment Encodes Glycoproteins with Homology to Herpes Simplex Virus Type 1 gD, gI and gE," J. Gen. Virol. 71: 2969-78.
Flowers et al., (1991) "Sequence Analysis of a Glycoprotein D Gene Homolog within the Unique Short Segment of the EHV-1 Genome," Virology 180: 175-84.
Bonass et al., (1991), "Identification of the EHV-1 SP17/18 as a Homologue of HSV-1 gD," Genbank Accession No. M60946.
Whalley, et al., (1990), "Identification and Comparative Sequence Analysis of a Gene in Equine Herpesvirus I with Homology to the Herpes Simplex Virus Glycoprotein D Gene," Genbank Accession No. M59773.
Mosher Mary E.
Research Corporation Technologies Inc.
Salimi Ali R.
LandOfFree
Immunogenic composition against equine herpesvirus type 1 does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Immunogenic composition against equine herpesvirus type 1, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Immunogenic composition against equine herpesvirus type 1 will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-324100