Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Fusion protein or fusion polypeptide
Patent
1995-06-06
1998-12-08
Guzo, David
Drug, bio-affecting and body treating compositions
Antigen, epitope, or other immunospecific immunoeffector
Fusion protein or fusion polypeptide
4242341, 4242651, 4242771, 4353201, 536 234, 536 241, A61K 3900, A61K 3902, C12N 1563, C07H 2104
Patent
active
058465405
ABSTRACT:
Immunogenic chimeric proteins comprising an endoplasmic reticulum signal sequence and at least one other peptide are disclosed. The invention relates to the design of vaccinia virus constructs capable of directing host organism synthesis of immunogenic chimeric proteins which can be used as immunogens, as vaccines, or in methods of treatment for cancer, infectious diseases, or autoimmune diseases.
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Bacik Igor
Bennink Jack R.
Restifo Nicholas P.
Rosenberg Steven A.
Yewdell Jonathan W.
Guzo David
Schwartzman Robert
The United States of America as represented by the Department of
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