Immunodominant 120 kDa surface-exposed adhesion protein genes of

Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Recombinant dna technique included in method of making a...

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435 697, 4352523, 4353201, 530350, 5303871, 536 231, 536 235, 536 234, 536 2433, 536 2431, 536 2432, 536 243, 536 245, 4242341, C12N 1500, C12N 1531, C07K 1400, A61K 3902

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060156910

ABSTRACT:
Disclosed is an isolated gene encoding a 120 kDa immunodominant antigen of Ehrlichia chaffeensis. The 120-kDa protein is one of the immunodominant proteins of E. chaffeensis that stimulates production of specific antibodies in infected humans. Also disclosed are the amino acid sequence of the 120 kDa antigen. Methods of producing a recombinant 120 kDa antigen and therapeutic methods of use of the antigen are also disclosed.

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