Immunodiagnostic test for syphilis and other treponemal infectio

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...

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435805, 435810, 436511, 436527, 436530, 436534, 436808, 436809, 436810, 530395, 530806, 530811, 530812, 530814, 530815, 530825, G01N 3353, G01N 33552, G01N 33544, C07K 1514

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048943282

ABSTRACT:
A component for the rapid detection of anti-Treponema pallidum antibodies adapted for use as a selective foundation material in standard immunoassays is provided. The component comprises a quantity of fibronectin insolubilized to a solid matrix. The fibronectin component provides a foundation material for the selective binding of antigenic outer membrane proteins extracted from Treponema pallidum. Incorporation of the insolubilized fibronectin component bound to the antigenic outer membrane proteins extracted from Treponema pallidum into a standard immunoassay test pack provides an immunological assay for the presence of respective complementary anti-Treponema pallidum antibody in a biological sample.

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