Immunodiagnostic reagent specific for legionella

Details Immunodiagnostic reagent specific for legionella Immunodiagnostic reagent specific for legionella

1990-07-05

1993-09-28

Kepplinger, Esther L.

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving antigen-antibody binding, specific binding protein...

43524027, 435960, 435975, 436518, 436804, 5303884, G01N 33569, C07K 1528

Patent

active

052485943

ABSTRACT:
A set of three unique monoclonal antibodies have been produced which recognize Legionella with particular specificity, without substantial cross-reactivity with non-Legionella bacteria. These monoclonal antibodies are useful as immunodiagnostic reagents for detecting Legionella.

REFERENCES:
patent: 4931547 (1990-06-01), Hoffman et al.
K. K. Sethi, "Monoclonal Antibodies Against Legionella pneumophila Serogroup 1 Antigens: Characterization and Their Potential Applications" in Monoclonal Antibodies Against Bacteria, pp. 121-136 (1985).
Helsel et al, Current Microbiology vol. 16: 201-208 (1988).
Plikaytis et al, "Purified 60-Kilodalton Legionella Protein Antigen with Legionella-Specific and Nonspecific Epitopes", J. Clin. Microbiol. 25(11) pp. 2080-2084 (Nov. 1987).
Nowinski et al, "Monoclonal Antibodies for Diagnosis of Infectious Diseases in Humans", Science 219 pp. 637-644 (11 Feb. 1983).
Edelstein, "Legionella" in Manual of Clinical Microbiology, 4th Ed. pp. 373-381 (1985).

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