Data processing: measuring – calibrating – or testing – Measurement system in a specific environment – Biological or biochemical
Patent
1998-06-12
2000-05-30
Carlson, Karen Cochrane
Data processing: measuring, calibrating, or testing
Measurement system in a specific environment
Biological or biochemical
530300, C07K 1400
Patent
active
060701269
ABSTRACT:
The present invention relates to identifying protein epitopes and more particularly to a novel method for identifying, determining the location, optimal length of amino acid residues and immunobiological potency of protein epitopes by applying a custom negative cosine function fit algorithm to a protein hydropathy scale. This fit analysis is supplemented with experimental immunobiological data. The amino acid sequence of the protein epitopes of the present invention exhibit a hydrophobic-hydrophilic-hydrophobic hydropathy pattern of an approximately fixed length in a given protein.
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Fritsche Herbert A.
Johnston Dennis A.
Kokolus William J.
Carlson Karen Cochrane
Ellis Howard M.
Fuierer Marianne
Kokolus William J.
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