Immunoassays to detect antiphospholipid antibodies

Chemistry: analytical and immunological testing – Involving an insoluble carrier for immobilizing immunochemicals

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422 57, 422 58, 435 71, 435 72, 435 78, 435 792, 435 793, 435 794, 435 795, 4352879, 436523, 436534, 436 71, 436822, 436823, 436829, G01N 33543

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057803196

ABSTRACT:
Liposome reagents used in assays to detect the presence or amount of an analyte in a test sample, particularly where the analyte is antiphospholipid antibodies are described. The liposome reagents comprise a liposome, a ligand chosen to bind specifically with the analyte and associated with the liposome membrane, and a haptenated component associated with the membrane of the liposome where the hapten is chosen to bind specifically to a receptor bound to a solid phase or to a label compound that is an element of a signal detection system and where the liposome reagent is prepared so that during the assay the linkage between the solid phase and ligand of the liposome reagent is maintained.

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Package Insert for Diastat Anti-Cardiolipin Kit. (Undated).
Package Insert for Diastat Total Anti-Cardiolipin Kit. (Undated).
Shield Diagnostics Ltd., Diastat Anti-Cardiolipin IgG and IgM Kit for in vitro diagnostic use 96 Test Kit. (Undated).

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