Immunoassays for the detection of antibodies to Chlamydia tracho

Details Immunoassays for the detection of antibodies to Chlamydia tracho Immunoassays for the detection of antibodies to Chlamydia tracho

1994-06-27

1996-05-14

Scheiner, Toni R.

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving antigen-antibody binding, specific binding protein...

435 736, 435 792, 435 793, 435 794, 435 795, 436518, 436530, 436531, 436534, G01N 33543, G01N 33569, G01N 33571

Patent

active

055166385

ABSTRACT:
The present invention provides methods for detecting the presence of antibodies to a microorganism (e.g., Chlamydia trachomatis) associated with a sexually transmitted disease in a biological sample, preferably urine. The methods of the invention comprise contacting the sample with an antigen from the microorganism and detecting the formation of an antigen-antibody complex.

REFERENCES:
patent: 4427782 (1984-01-01), Caldwell, et al.
patent: 4766065 (1988-08-01), Mosier et al.
patent: 5085986 (1992-02-01), Mauck et al.
patent: 5122446 (1992-06-01), Friedman-Kien et al.
Pudakkainen et al., "Chlamydial Pneumonitis and Its Serodiagnosis in Infants", J. Infect. Dis., 149(4):598-604 (Apr. 1984).
Paul et al. "Evaluation of Three Chlamydia trachomatis Immunoassays with an unbiased, Noninvasive Clinical Sample", J. Clin. Microbiol., 28(2):220-222 (Feb. 1990).
Morse et al, "Sexually Transmitted Diseases", pp. 863-868 in Manual of Clinical Microbiology. 4th Ed. (1985).
Dorland's Illustrated Medical Dictionary, p. 822, W. B. Saunders Company (1985).
Caldwell, H. D., et al., "Purification and Partial Characterization of the Major Outer Membrane Protein of Chlamydia trachomatis", Infection and Immunity, vol. 31, No. 3, pp. 1161-1176, Mar. 1981.

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