Immunoassays for insulin sensitivity enhancers, insulin sensitiv

Details Immunoassays for insulin sensitivity enhancers, insulin sensitiv Immunoassays for insulin sensitivity enhancers, insulin sensitiv

1993-09-07

1995-11-14

Ceperley, Mary E.

Chemistry: analytical and immunological testing

Involving an insoluble carrier for immobilizing immunochemicals

436531, 436532, 436533, 436534, 436546, 436548, 436815, 5303889, G01N 33577, C07K 1644

Patent

active

054666104

ABSTRACT:
Methods have been developed to produce novel compounds by covalently coupling thiazolidinedione insulin sensitivity enhancers (ISEs) to proteins. These novel compounds are well suited for producing antibodies, which are specific for thiazolidinedione ISEs and which are well suited for fluorescent immunoassays of thiazolidinedione and non-thiazolidinedione ISEs in buffers and biological tissues. Antibodies also are well suited for high-volume screening for immunologically related novel, non-thiazolidinedione and thiazolidinedione ISEs.

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