Immunoassays for anti-HCV antibodies employing combinations of h

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving virus or bacteriophage

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

436518, 436820, C12Q 170, G01N 33576

Patent

active

057120870

ABSTRACT:
Combinations of HCV antigens that have a broader range of immunological reactivity than any single HCV antigen. The combinations consist of an antigen from the C domain of the HCV polyprotein, and at least one additional HCV antigen from either the NS3 domain, the NS4 domain, the S domain, or the NS5 domain, and are in the form of a fusion protein, a simple physical mixture, or the individual antigens commonly bound to a solid matrix.

REFERENCES:
patent: 4464474 (1984-08-01), Coursaget
patent: 4701721 (1987-10-01), Kupers
patent: 5106726 (1992-04-01), Wang
patent: 5308750 (1994-05-01), Mehta et al.
patent: 5350671 (1994-09-01), Houghton et al.
patent: 5436126 (1995-07-01), Wang et al.
Bradley et al., Posttransfusion Non-A, Non-B Hepatitis in Chimpanzees Physiochemical Evidence That the Tubule-Forming Agent Is a Small, Enveloped Virus. Gastoenterology 88:773-779, 1985.
Choo et al., "Isolation of a cDNA clone derived from a blood borne non-A, non-B viral hepatisis genome" Science (1989) 244:359-362.
Geysen et al., "Use of peptide synthesis to probe viral antigens for epitopes to a resolution of a single amino acid" Proc. Natl. Acad. Sci. USA (1984) 81:3998-4002.
Kuo et al., "An assay for circulating antibodies to a major etiologic virus of human non-A, non-B hepatitis" Science (1989) 244:362-264.
Krawczynski et al., "Hepatitis C virus antigen in hepatocytes: Immunomorphologic detection and identification" Gastroenterology (1992) 103:622-629.
Saito et al., "Performance of an enzyme-linked immunosorbent system for antibodies to hepatitis C virus with two new antigens (c11/c7)" Clin. Chem. (1992) 38(12):2434-2439.
Sallberg et al., "Immunodominant regions within the hepatitis C virus core and putative matrix proteins" J. Clin. Microbiol. (1992) 30(8):1989-1994.

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Immunoassays for anti-HCV antibodies employing combinations of h does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Immunoassays for anti-HCV antibodies employing combinations of h, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Immunoassays for anti-HCV antibodies employing combinations of h will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-340719

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.